Naslov
Investigation of the effect of beer with Ganoderma lucidum on blood pressure and heart rate in young men

Autori
Despotović, Saša ; Platiša, Mirjana M. ; Veljović, Mile ; Nedović, Viktor ; Velić, Natalija ; Gorenšek, Janez ; Gojković-Bukarica, Ljiljana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
International Medicinal Mushroom Conference IMMC11 Electronic Abstract Book / - Beograd, 2022, 151-151

Skup
International Medicinal Mushroom Conference (IMMC11)

Mjesto i datum
Beograd, Srbija, 27.09.2022. - 30.09.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
alcohol ; beer ; heart rate ; Ganoderma lucidum ; electrocardiography ; adult

Sažetak
A large number of studies have dealt with the effect of alcohol on the cardiovascular system. It is assumed that there is no significant difference between the alcoholic beverages consumed but that the only relevant parameter is the amount of alcohol consumed, i.e., its positive effect on the cardiovascular system in cases of moderate consumption. No consensus has been reached at the world level on safe amounts of alcohol, but each country has its guidelines. In most countries, recommended daily doses for men range from 10 to 40 g, limited to a maximum of 160 g per week. These values are reduced to 8 and 20 g per day for women. In this regard, the Institute for Mental Health of Serbia recommends up to two alcoholic drinks per day (330 ml of 5% beer) for men and one for women. Pharmacological in vivo studies were conducted on 18 men aged 26±1, whose body fat index was 24, 5±0, 5 kg/m2. They were all in good general health, with no symptoms or history of heart disease, hypertension, or diabetes, a normal clinical picture, and no addiction problems. All examinations were conducted under the Ethics Committee of the Faculty of Medicine in Belgrade, while each individual voluntarily signed the consent for participation. Electrocardiogram, heart rate, systolic and diastolic blood pressure were recorded. Furthermore, the time between the depolarization of ventricles until their repolarization (the QT interval) and time between two successive ventricular depolarizations (the RR interval) were determined. The obtained results show that, immediately after consumption, control, and beer, there is a sudden jump in heart rate, diastolic and systolic blood pressure. However, after ten minutes, their values return to the initial level. By analyzing the obtained electrocardiograms, it can be seen that the QT variability was significantly increased after beer consumption with Ganoderma lucidum extract, after which it returned to normal. This drink has an acute and delayed effect on the entire cardiovascular system, which could be monitored through changes in blood pressure and heart rate. The results also indicate a decrease in the parasympathetic control of the heart and altered dynamics of the QT interval.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija, Prehrambena tehnologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

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