Naslov
Sex differences in effects of eight-week increment aerobic exercise program on bone metabolism in young non-athletes

Autori
Davidović Cvetko, Erna ; Nešić, Nebojša ; Matić, Anita ; Milas Ahić, Jasminka ; Drenjančević, Ines

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
3rd Regional Congress of Physiological Societies and 5th Congress of Croatian Physiological Society - Book of Abstracts / - , 2022, 18-18

Skup
3rd Regional Congress of Physiological Societies ; 5th Congress of Croatian Physiological Society

Mjesto i datum
NP Plitvička jezera, Hrvatska, 22.09.2022. - 24.09.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Aerobic exercise ; bone turnover ; biomarkers of bone metabolism ; sex differences

Sažetak
Purpose: Regular exercise and physical activity play an important role in preserving bone health, mass, and strength. However, it remains unclear how much load is necessary and for how long should it be applied in order to induce bone remodeling. Evidence on the influence of interval aerobic training with variations in intensity to the bone remodeling process is scarce. Thus, the main goal of this study was to explore if there was an effect of the short- term aerobic exercise program on the bone remodeling process and if there were sex differences in the effect of the training program on bone metabolism. Methods: Twenty-one participants (11 men and 10 women) aged 20-23 performed an eight-week aerobic exercise program three times per week in one-hour sessions with increases in the exercise load every two weeks. Bone density, bone mineral content and concentration of markers of bone metabolism: osteocalcin, C-terminal procollagen type I peptide, pyridinoline, parathyroid hormone, osteoprotegerin, and the receptor activator of nuclear kappa B ligand by ELISA were measured at the start and at the end of the study. Results: The aerobic exercise program increased the concentration of osteocalcin (11.34 vs 14.24 ng/ml), pyridinoline (67.51 vs 73.99 nmol/l), and the receptor activator of nuclear kappa B ligand (95.122 vs 158.15 pg/ml). A statistically significant increase in bone density at neck mean (1.122 vs 1.176 g/cm3 ) and in bone mineral content at dual femur (33.485 vs 33.700 g) was found in women, while there was no statistically significant change at any site in men. Conclusion: The interval aerobic exercise protocol implemented for 8 weeks affected the bone remodeling process, which was evident from the increase in concentration of some bone remodeling biomarkers. The results also revealed different effects of the exercise program on the bone metabolism in men vs women.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA