Pregled bibliografske jedinice broj: 1227162
Construction of chiral Betti base precursors containing a congested quaternary stereogenic center via chiral phosphoric acid-catalyzed arylation of isoindolinone-derived ketimines
Construction of chiral Betti base precursors containing a congested quaternary stereogenic center via chiral phosphoric acid-catalyzed arylation of isoindolinone-derived ketimines // New journal of chemistry, 46 (2022), 18; 8760-8764 doi:10.1039/d2nj00493c (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1227162 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Construction of chiral Betti base precursors containing a congested quaternary stereogenic center via chiral phosphoric acid-catalyzed arylation of isoindolinone-derived ketimines
Autori
Glavač, Danijel ; Gredičak, Matija
Izvornik
New journal of chemistry (1144-0546) 46
(2022), 18;
8760-8764
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Friedel-Crafts reaction ; electron-rich phenols ; enantioselective construction ; asymmetric-synthesis ; aminonaphthols ; 2-naphthols ; naphthols ; ligands
Sažetak
Synthesis of enantioenriched Betti base precursors containing a congested quaternary stereocenter is described. In a chiral phosphoric acid-catalyzed reaction, a series of in situ generated isoindolinone-derived ketimines and phenol derivatives yield products in good to excellent yields, and moderate enantioselectivities. Conversion of the obtained products into chiral Betti bases with the retention of the optical purity is demonstrated.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
