Naslov
Sleep symptoms are essential features of long-COVID – Comparing healthy controls with COVID-19 cases of different severity in the international COVID sleep study (ICOSS-II)

Autori
Merikanto, Ilona ; Dauvilliers, Yves ; Chung, Frances ; Wing, Yun Kwok ; de Gennaro, Luigi ; Holzinger, Brigitte ; Bjorvatn, Bjørn ; Morin, Charles M ; Penzel, Thomas ; Benedict, Christian ; Koscec Bjelajac, Adrijana ; Chan, Ngan Yin ; Espie, Colin A ; Hrubos-Strøm, Harald ; Inoue ; Yuichi ; Korman, Maria ; Landtblom, Anne-Marie ; Léger, Damien ; Matsui, Kentaro ; Mota-Rolim, Sergio ; Nadorff, Michael R ; Plazzi, Giuseppe ; Reis, Catia ; Yordanova, Juliana ; Partinen, Markku

Izvornik
Journal of sleep research (0962-1105) 32 (2022), 1; E13754, 7

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
COVID-19, excessive daytime sleepiness, fatigue, insomnia, pandemic, post-acute sequelae ofCOVID-19

Sažetak
Many people report suffering from post-acute sequelae of COVID-19 or “long-COVID”, but there are still open questions on what actually constitutes long-COVID and how prevalent it is. The current definition of post-acute sequelae of COVID-19 is based on voting using the Delphi-method by the WHO post-COVID-19 working group. It emphasizes long-lasting fatigue, shortness of breath and cognitive dysfunction as the core symptoms of post-acute sequelae of COVID-19. In this international survey study consisting of 13, 628 subjects aged 18–99 years from 16 countries of Asia, Europe, North America and South America (May–Dec 2021), we show that postacute sequelae of COVID-19 symptoms were more prevalent amongst the more severe COVID-19 cases, i.e. those requiring hospitalisation for COVID-19. We also found that long-lasting sleep symptoms are at the core of post-acute sequelae ofCOVID-19 and associate with the COVID-19 severity when COVID-19 cases are compared with COVID-negative cases. Specifically, fatigue (61.3%), insomnia symp-toms (49.6%) and excessive daytime sleepiness (35.8%) were highly prevalent amongst respondents reporting long-lasting symptoms after hospitalisation forCOVID-19. Understanding the importance of sleep-related symptoms in post-acute sequelae of COVID-19 has a clinical relevance when diagnosing and treating long-COVID.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita, Psihologija

POVEZANOST RADA