Naslov
Abnormal glandular cells in a cervical smear

Autori
Jurič, Danijela ; Ovanin-Rakić, Ana ; Audy-Jurković, Silvana ; Kani, Dubravka ; Ilić-Forko, Jadranka ; Buković, Damir

Izvornik
Cytopathology (0956-5507) 17 (2006), 5; 299-300

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Abnormal glandular cells, Pap smear

Sažetak
Minimal-deviation adenocarcinoma (MDA), previously known as adenoma malignum, 1 is a fully malignant invasive adenocarcinoma of the cervix in which neoplastic cells have a deceptively benign cytological appearance. The tumour is often diagnosed at an advanced stage because initial superficial biopsies may be misinterpreted as benign. The diagnosis of carcinoma is often established only after the patient has undergone deep conization or hysterectomy because the depth of penetration of the glands is the key histological feature of MDA. Although all these tumours in the original description were extremely well differentiated endocervical adenocarcinomas, MDA has been expanded to include the endometrioid and clear-cell variants.2, 3 MDA accounts for 1–3% of all cervical adenocarcinoma cases.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA