Naslov
Synthesis and exploration of 1,3-dipolar cycloaddition reactions of guanidine azides

Autori
Štrbac, Petar ; Margetić, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
27th Croatian Meeting of Chemists and Chemical Engineers and 5th Symposium Vladimir Prelog : Book of Abstracts / Marković, Dean ; Meštrović, Ernest ; Namjesnik, Danijel ; Tomašić, Vesna - Zagreb : Hrvatsko kemijsko društvo, 2021, 271-271

Skup
27. hrvatski skup kemičara i kemijskih inženjera (27HSKIKI) ; 5. simpozij Vladimir Prelog

Mjesto i datum
Veli Lošinj, Hrvatska, 05.10.2021. - 08.10.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
guanidine ; Diels-Alder reaction ; 1, 3-dipolar cycloadditions ; triazole ; azides

Sažetak
Novel guanidine azides protected by the tert-butyloxycarbonyl (Boc) groups were prepared and subjected to cycloaddition reactions in order to establish their reactivity and synthetic suitability as guanidine cycloaddition ‘delivery’ reagents. Thermal reactions without catalysts and copper catalyzed 1, 3-dipolar cycloadditions (CuAAC) were applied in conjuction with various dipolarophiles and alkynes. Sharpless ‘click’ reaction has been shown as synthetically very suitable and applied reactions conditions are compatible with Boc-guanidine functional group, providing corresponding 1, 4-disubstituted [1, 2, 3]-triazole linked products.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA