Naslov
Elevation of serum total triiodothironine and free triiodothironine in Croatian veterans with combat-related post-traumatic stress disorder

Autori
Karlović, Dalibor ; Kozarić-Kovačić, Dragica ; Kocijan-Hercigonja, Dubravka

Izvornik
Military medicine (0026-4075) 167 (2002), 10; 846-849

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
combat-related PTSD; triiodohironine; Croatian veterans

Sažetak
Objective: To asses possible differences in serum-free triiodo-thironine (FT3), total triiodothironine (TT3), free thyroxine, total thyroxine, and thyroid-stimulating hormone levels between male combat veterans with chronic post-traumatic stress disorder and healthy male control subjects. Method: Male combat veterans (N = 38 ; ages 23-53 years ; mean +/- SD = 35.9 +/- 7.5 years) with chronic post-traumatic stress disorder (duration of illness was 2-6 years ; mean +/- SD = 3.53 +/- 0.95 years) were compared with healthy male control subjects (N = 32 ; ages 25-50 years ; mean +/- SD = 36.5 +/- 8.3 years). Serum samples were analyzed by luminoimmunochemical assays for basal levels of thyroid-stimulating hormone, total thyroxine, TT3, free thyroxine, and FT3. Results: Combat veterans with chronic combat-related post-traumatic stress disorder had significantly increased values of FT3 (mean +/- SD, 5.92 +/- 1.11 ; t = 2.27 ; p < 0.02), as well as TT3 (mean +/- SD, 2.04 +/- 0.32 ; t = 6.26 ; p < 0.0001) than the control group. Conclusion: Elevated serum TT3 and FT3 are associated with chronic combat-related post-traumatic stress disorder.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA