Naslov
Acute Heart Failure Developed as Worsening of Chronic Heart Failure is Associated with Increased Mortality Compared to De Novo Cases

Autori
Degoricija, Vesna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts. XIth Mediterranean Emergency Medicine Congress (MEMC). / Moreno, Lisa - St. Julian's : American Academy of Emergency Medicine, 2022, 49-49

Skup
XIth Mediterranean Emergency Medicine Congress (MEMC22)

Mjesto i datum
San Ġiljan, Malta, 21.09.2022. - 24.09.2022

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
acute heart failure ; chronic heart failure ; mortality

Sažetak
Acute heart failure (AHF) emerges either de novo or from worsening of chronic heart failure (CHF). The aim of the present study was to evaluate the association between worsening of CHF and mortality in AHF patients. Out of 152 included AHF patients, 47 (30.9%) were de novo AHF patients and 105 (69%) were AHF patients with worsening of CHF. The proportion dying in hospital (19.0% vs. 4.3%, p=0.023) and within 3 months after hospitalization (36.6% vs. 6.7%, p<0.001) was signifcantly higher in AHF patients with worsening of CHF. Logistic regression analyses also showed a signifcant positive association of AHF emerging as worsening of CHF with hospital mortality [odds ratio (OR) and 95% confdence interval (CI): 5.29 (1.46–34.10), p=0.029] and 3-month mortality [8.09 (2.70–35.03), p=0.001]. While the association with hospital mortality was no longer signifcant after adjusting for comorbidities and clinical as well as laboratory parameters known to be associated with mortality in heart failure patients, the association with 3- month mortality remained signifcant. We conclude that compared to de novo AHF, AHF evolved from worsening of CHF is a more severe condition and is associated with increased mortality.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA