Naslov
Stupnjevanje invazivnih stanica-pregled
(Invasive cell grading-an overview)

Autori
Ivkić, Mirko ; Bedeković, Vladimir ; Kalogjera, Livije ; Čupić, Hrvoje ; Ferenčić, Željko

Izvornik
Acta clinica Croatica (0353-9466) 41 (2002), 3; 233-236

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
carcinoma-diagnosis; carcinoma-pathology; carcinoma-prognosis

Sažetak
Pathohistologic diagnosis plays a pivotal role in therapeutic modalities for cancer, and acts as a prognostic factor. The histologic grade is a numeric expression of tumor differentiation and is linked to patient outcome. Broders' scoring system is still widely used in scoring squamous cell carcinoma. New data suggest that in the most invasive part of a malignant tumor, the morphology and biologic behavior differ from the central and superficial areas of the same tumor. A new invasive cell grading system has been proposed as a better prognostic factor in the multifactorial diagnostic and therapeutic approach to the patient with malignant tumor. Numerous studies performed to date have provided sufficient evidence to propose the invasive cell grading system to be introduced instead of the 'old' Broders' scoring system.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA