Naslov
Cytologic and immunoenzymatic findings in CSF from patients with tick-borne encephalitis

Autori
Jeren , T. ; Vince, A.

Izvornik
Acta cytologica (0001-5547) 42 (1998), 2; 330-4

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Sažetak
OBJECTIVE: To evaluate the dynamics of cytologic changes in the cerebrospinal fluid (CSF) of patients with tick-borne encephalitis (TBE) and to determine the various forms of mononuclear cells by immunocytochemical methods. STUDY DESIGN: To perform a cytologic analysis of 200 cells in stained sediment of CSF. To determine the population and subpopulation of mononuclear cells by using monoclonal antibodies. RESULTS: Pleocytosis in CSF in patients with TBE during the first three days of illness was, on average, 570 cells per cubic millimeter with about 60% neutrophils. Mononuclear cells predominated from the fifth day of illness. Among lymphoid cells, 18% carried marker CD20 and 60% of them marker CD3. Among monocytoid cells, 66% carried marker CD32. CONCLUSION: CSF cytology findings reflect the immunologic and inflammatory changes in the CNS during TBE.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA