Naslov
Abnormal uterine bleeding and severe anaemia as a cause of life threatening condition.

Autori
Culej Diana, Planinić Radoš Gordana, Duić Željko, Bursać Danijel

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
4. Hrvatski kongres menopauzalne medicine s međunarodnim sudjelovanjem. / - , 2022, 26-26

Skup
4. Hrvatski kongres menopauzalne medicine s međunarodnim sudjelovanjem.

Mjesto i datum
Zagreb, Hrvatska, 06.10.2022. - 07.10.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Recenziran

Ključne riječi
abnormal uterine bleeding, severe anaemia

Sažetak
The World Health Organisation (WHO) defines anaemia as a global public health problem. It is medical condition in which the number of red blood cells or the haemoglobin concentration within them is below the physiological range. It can be manifested with symptoms of weakness, malaise, fatigue, shortness of breath, tachycardia and skin pallor. We present a case of 40-year-old women with abnormal uterine bleeding (AUB) accompanied by malaise, weakness and tachycardia. The patient described heavy menstrual bleeding for the last 14 days. On clinical examination, the patient appeared oriented and with pale skin. Her vitals were 100/60 mmHg, heart rate 108 and respiratory rate 16. The abdomen was soft and non-tender to palpation. Speculum examination revealed that the bleeding was from the uterus. There was no pathological founding’s during gynaecological and transvaginal ultrasound examination. Complete blood count performed at the time of her arrival showed low haemoglobin of 24 g/L, a low haematocrit of 7, 4%, a mean corpuscular volume of 98, 7 fL and a number of red blood cells 0, 75x1012/L. The patient's international normalized ratio was 1, 7, prothrombin was 0, 45 and fibrinogen 1, 4. Due to the severity of the anaemia, she was given 6 units of red blood cell transfusion, 2 fresh frozen plasmas and tranexamic acid with calcium carbonate. The curettage was performed. Pathohistological finding was endometrium in proliferation. Afterwards, the haemoglobin level improved to 90 g/L. Past medical history revealed that she abused alcohol. On an abdominal CT scan, alcohol related liver disease (ARLD) was confirmed. The liver plays a key role in blood coagulation and is involved in both primary and secondary haemostasis. We should keep in mind that coagulopathy is the underlying cause of abnormal uterine bleeding and that anaemia must be analysed for successful treatment. A multidisciplinary approach of anemia caused by AUB is required in cases of severe anemia. In complicated cases like this, it is advisable to cooperate with doctors of other specialties, such as gastroenterologists and hepatologists.

Izvorni jezik
Engleski

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