Naslov
Necrotizing scleritis associated with rheumatoid arthritis

Autori
Galić, Petra ; Babić, Fran ; Matić, Lucija ; Galić, Dora ; Kurtović, Anamaria ; Bačun, Barbara ; Matić, Suzana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Knjiga sažetaka / Pavlović, Vedrana ; Jurić, Ivana ; Prigl, Ivan - Osijek, 2022, 72-72

Skup
4th International Translational Medicine Congress of Students and Young Physicians (OSCON 2022)

Mjesto i datum
Osijek, Hrvatska, 31.03.2022. - 02.04.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
biologic therapy ; rheumatoid arthritis ; scleritis

Sažetak
In patients with rheumatoid arthritis (RA), necrotizing scleritis is a result of a systemic vasculitic reaction. It is associated with severe ocular morbidity, even with eye perforation and necessity for urgent enucleation. We present a 68 year old female on systemic therapy including corticosteroids, methotrexate, and sulfasalazine for RA for twenty years. She was admitted to the ophthalmology department and was diagnosed with progressive monocular scleritis and peripheral ulcerative keratitis of the right eye and initial conjunctival hyperemia on left. She was prescribed corticosteroid eye drops and an increased amount of oral prednisolone. Despite treatment, the peripheral corneal thinning and superonasal elevated and pigmented lesion in the peripheral iris which resembled an intraocular tumor appeared through the thinned sclera. This resulted in perforation which was urgently closed with a triple amniotic membrane. Due to exacerbation, biologic therapy with adalimumab was started and a patient had a positive clinical answer. Further corneoscleral thinning and the possibility for future perforations were minimalized.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA