Naslov
USE OF ROPIVACAINE FOR SUPERFICIAL CERVICAL BLOCK: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND STUDY

Autori
Ozegic, Ognjen ; Bodulica, Bruna ; Pazur, Iva ; Lijovic, Lada ; Zagorac, Dorotea ; Radocaj, Tomislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Acta Clin Croat 2022 ; 61(Suppl 1):174 / - , 2022, 174-174

Skup
8 međunarodni stručno-znanstveni skup: Zaštita na radu i zaštita zdravlja

Mjesto i datum
Zagreb, Hrvatska, 02.09.2022. - 03.09.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Ropivacaine

Sažetak
Background: Carotid endarterectomy is often indicated in patients suffering from multiple chronic conditions. Apart from general anesthesia, this surgical procedure can be performed with the use of superficial cervical block. This anesthesiological approach makes it possible to promptly recognize neurological deficits that are known to happen during the procedure, enabling swift surgical reaction. Ropivacaine is a local anesthetic that has shown good safety record in regards to neurotoxicity and cardiotoxicity. The study hypothesis is that ropivacaine mixed with lidocaine provides a block that has faster onset and longer duration of action compared to mixture of levobupivacaine and lidocaine, simultaneously offering the same quality of infiltration anesthesia. Material and methods: The anesthetic mixture for superficial cervical block was composed of lidocaine in fixed dose of 200 mg, and of a second local anesthetic. Patients (N=30) were randomly divided into two groups. Ropivacaine 2 mg/kg was used as the second local anesthetic. in the experimental group (N=15), whereas the control group received levobupivacaine 2 mg/kg instead (N=15). Normal saline was added so the mixture measured 50 mL total. After the neck was infiltrated using the appointed mixture, several values were measured: onset time and total duration of sensory block, and pain assessment was made using the NPRS scale each 2 hours during 12 hours in total. The analysis was performed using propensity score matching with optimal pairing without switching and using the closest neighbor method 1:1 with distance calculated using logical regression. Results: The results showed that there were no statistically significant differences regarding block onset time (p=0.148), total block duration (p=0.775), need for additional analgesia (p=0.831), nor NPRS scores (p=0.456). Conclusions: Being perceived as one of the local anesthetics with the least side effects, ropivacaine is undoubtedly worth to be considered a drug of choice for performing regional anesthetic procedures. The results of this study are encouraging. Ropivacaine showed similar anesthetic properties as levobupivacaine, simultaneously possessing possible advantage of having favorable neurotoxic and cardiotoxic profile.

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne prirodne znanosti, Temeljne medicinske znanosti, Kliničke medicinske znanosti, Integrativna bioetika (prirodne, tehničke, biomedicina i zdravstvo, biotehničke, društvene, humanističke znanosti), Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA