Pregled bibliografske jedinice broj: 1210608
Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4- dihydroquinazolin2-yl)thio)acetate
Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4- dihydroquinazolin2-yl)thio)acetate // Molbank, 2022 (2022), M1434, 5 (međunarodna recenzija, članak, znanstveni)
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Naslov
Methyl 2-((3-(3-methoxyphenyl)-4-oxo-3,4-
dihydroquinazolin2-yl)thio)acetate
Autori
Molnar, Maja ; Komar, Mario ; Jerković, Igor
Izvornik
Molbank (1422-8599) 2022
(2022);
M1434, 5
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
quinazolinone ; green chemistry ; alkylation
Sažetak
A green synthetic procedure was developed for the two-step synthesis of methyl 2-((3- (3-methoxyphenyl)-4-oxo-3, 4-dihydroquinazolin-2- yl)thio)acetate from anthranilic acid, using two green chemistry approaches: utilization of the DES and microwave-induced synthesis. The first step includes a synthesis of 2-mercapto-3-(3- methoxyphenyl)quinazolin-4(3H)-one which was performed in choline chloride:urea DES. In the second step S- alkylation of 2-mercapto-3-(3- methoxyphenyl)quinazolin4(3H)-one was performed in a microwave-induced reaction. The desired compound was successfully obtained in a yield of 59% and was characterized by different spectral methods.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
HRZZ-UIP-2017-05-6593 - Zelene tehnologije u sintezi heterocikličkih spojeva (GREENNESS) (Molnar, Maja, HRZZ ) ( CroRIS)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Emerging Sources Citation Index (ESCI)
- Scopus
