Naslov
Could mental and physical exercise alleviate Alzheimer's disease?

Autori
Radić, Borislav ; Blažeković, Antonela ; Duraković, Din ; Jurišić-Kvesić, Anka ; Borovečki, Fran ; Bilić, Ervina

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), stručni

Izvornik
Psychiatria Danubina, 33 (2021), Suppl 4 / - , 2021, 1267-1273

Skup
29th Danubian psychiatric symposium and IX Croatian congress on psychopharmacotherapy

Mjesto i datum
Online ; Zagreb, Hrvatska, 18.03.2021. - 20.03.2021

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Alzheimer's dementia ; mental activity ; physical activity ; personalized medicine

Sažetak
The aim of this review is to emphasize the importance of mental activity and aerobic physical exercise as one of the most important health- related activities which may delay the onset or slow down the progression of Alzheimer's dementia. Studies have shown that the elderly who regularly engage in mental and physical activities have a lower risk of dementia development. Performing mental and physical activities regularly has a synergistic effect on the improvement of cognitive functions. Complex mental activity during life is associated with a reduction in the hippocampal atrophy rate, which is a sensitive early-stage biomarker of dementia while regular physical exercise can slow down the progressive reduction of the cortical brain volume which occurs during aging. Mental activity increases a person's "cognitive reserve" and promotes the formation of new communications between brain cells. Since it is not possible to influence genetic components of Alzheimer's dementia, preventative interventions such as encouraging regular engagement in mental and physical activities are extremely important. Activities need to be safe, moderate, comfortable, and adapted as to type, duration, and especially the health and functional status of the patient. In the near future, it is expected that genome analysis in personalized medicine will guide us in the right direction on certain types of physical and mental exercise.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA