Naslov
Hospital readmission rate and mortality after severe exacerbation of chronic obstructive pulmonary disease

Autori
Pavlisa, Gordana ; Puretic, Hrvoje ; Dzubur, Fedja ; Labor, Marina ; Vukic Dugac, Andrea ; Hecimovic, Ana ; Jankovic, Mateja ; Jakopovic, Marko ; Samarzija, Miroslav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Hospital readmission rate and mortality after severe exacerbation of chronic obstructive pulmonary disease / - : European Respiratory Society, 2017, 61-61

Skup
ERS International Congress 2017

Mjesto i datum
Milano, Italija, 09.09.2017. - 13.09.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
COPD, acute exacerbation

Sažetak
Background: It is well known that acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are associated with increased morbidity, readmission rates and mortality, but few studies report rehospitalization and mortality rate after severe AECOPD treated in intensive care unit (ICU). The aim of our study was to assess two year readmission rates and mortality in AECOPD patients treated in ICU and to identify determinants of these outcomes. Methods: 55 patients (35 men) mean age 68.1 (±10.5) years successfully treated in respiratory ICU due to AECOPD and discharged from hospital were included in the study. Patients demographics, hematology, biochemistry and arterial blood gases on the first treating day were recorded. Results: During the median follow-up of 2.4 years, 29 (46.8%) patients had one or more readmissions due to AECOPD. The average number of readmissions was 1.2. Significant predictors for the time to next hospitalization were initial PaCO2, fibrinogen, proteins and alpha 2 globulins (p=0.001 for the overall model fit). Significant predictors for the number of readmissions were: age at admission, neutrophil count, serum sodium, bilirubin, coronary artery disease (p=0.001 for the overall model fit). During the follow-up, 21 (38.2%) patients died. Significant predictors for survival time after incident hospitalization were: BMI, monocyte count, serum LDH, cancer and hypertension (p<0.001 for the overall model fit). Conclusion: Our study suggests that patient age, comorbidity, BMI and certain biochemistry parameters are potential predictors of readmission and poor outcome after AECOPD treated in ICU. Further studies are needed to verify our findings.

Izvorni jezik
Engleski

POVEZANOST RADA