Naslov
Non Covalent Interaction in Development of Innovative pharmaceutical product – current status and way forward

Autori
Meštrović, Ernest

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Supramolecular Chemistry 2021 web site (https://supramolchem.org/) / - , 2021, 1-1

Skup
4. simpozij supramolekulske kemije

Mjesto i datum
Zagreb, Hrvatska, 10.12.2022

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
Non-covalent interactions ; drug – target interaction ; drug product, drug discovery, drug development
(Non-covalent interactions ; drug – target interaction ; drug product, drug discovery, drug developmen)

Sažetak
It is well know that Non-covalent interactions are critical in maintaining the three-dimensional structure of large molecules, such as proteins and nucleic acids and this fact was and is used in the understanding drug – target interaction. This is basis for many New Chemical Entity discover program over Industrial and Academia. Beside this there is also space for utilization of non- covalent interaction in development or improvement of property of existing drug of to increase performance of drug product. Non covalent interaction can be connect with solid state property and with this one can start with design proper crystal property. From another aspect non covalent interaction is very important for understanding interaction in solution which open space for design of drug delivery system based on understanding interaction on molecular level in the drug product. The scope of this lecture is to present current trend and share vision about role of supramolecular chemistry in the future of drug discovery and development.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Interdisciplinarne prirodne znanosti, Farmacija

POVEZANOST RADA