Naslov
Results of the Croatian Primary Percutaneous Coronary Intervention Network for Patients With ST- Segment Elevation Acute Myocardial Infarction

Autori
Nikolić Heitzler, Vjeran ; Babić, Zdravko ; Milicic, Davor ; Bergovec, Mijo ; Raguz, Miroslav ; Mirat, Jure ; Strozzi, Maja ; Plazonic, Zeljko ; Giunio, Lovel ; Steiner, Robert ; Starcevic, Boris ; Vukovic, Ivica

Izvornik
The American Journal of Cardiology (0002-9149) 105 (2010); 1261-1267

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Acute myocardial infarction, Reperfusion therapy, Thrombolysis, Primary angioplasty, Europe, Mortality, Incidence

Sažetak
The Republic of Croatia, with a gross domestic product per capita of US$11, 554 in 2008, is an economically less-developed Western country. The goal of the present investigation was to prove that a well-organized primary percutaneous coronary intervention network in an economically less-developed country equalizes the prospects of all patients with acute ST-segment elevation myocardial infarction at a level comparable to that of more economically developed countries. We prospectively investigated 1, 190 patients with acute STsegment elevation myocardial infarction treated with primary PCI in 8 centers across Croatia (677 nontransferred and 513 transferred). The postprocedural Thrombolysis In Myocardial Infarction flow, in-hospital mortality, and incidence of major adverse cardiovascular events (ie, mortality, pectoral angina, restenosis, reinfarction, coronary artery bypass graft, and cerebrovascular accident rate) during 6 months of follow-up were compared between the nontransferred and transferred subgroups and in the subgroups of older patients, women, and those with cardiogenic shock. In all investigated patients, the average door-to-balloon time was 108 minutes, and the total ischemic time was 265 minutes. Postprocedural Thrombolysis In Myocardial Infarction 3 flow was established in 87.1% of the patients, and the in-hospital mortality rate was 4.4%. No statistically significant difference was found in the results of treatment between the transferred and nontransferred patients overall or in the subgroups of patients >75 years, women, and those with cardiogenic shock. In conclusion, the Croatian Primary Percutaneous Coronary Intervention Network has ensured treatment results of acute ST-segment elevation myocardial infarction comparable to those of randomized studies and registries of more economically developed countries

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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