Naslov
ANALYSIS OF VITAMIN D LEVELS IN PATIENTS WITH ORAL LICHEN PLANUS

Autori
Draganja, Mirna ; Družijanić, Ana ; Glavina, Ana ; Cigić Livia

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Acta stomatologica Croatica / Klarić Sever, Eva - Zagreb, 2022, 194-194

Skup
8. Međunarodni kongres Stomatološkog fakulteta Sveučilišta u Zagrebu

Mjesto i datum
Rovinj, Hrvatska, 08.04.2022. - 09.04.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Oral lichen planus ; Vitamin D ; Oral cancer
(oral lichen planus ; vitamin D ; oral cancer)

Sažetak
Introduction: The aim of this study was to examine whether there is a difference in the values of serum vitamin D concentration between subjects with OLP and subjects without pathological changes in the oral mucosa. Subjects and Methods: Patient medical data included age, gender, and smoking status (n = 68). Blood samples were taken from each subject to determine the levels of serum vitamin D concentration. The study group consisted of 34 subjects diagnosed with OLP (28 with erosive and 6 with non-erosive form), and the control group consisted of 34 subjects without pathological changes in the oral mucosa. Results: The results confirmed a statistically significant difference in serum vitamin D levels between patients with erosive OLP and healthy control subjects (P = 0, 045). No statistically significant difference was found between the serum vitamin D concentration in subjects with erosive versus non-erosive form. Serum vitamin D levels showed a statistically significant difference between the level of vitamin D in the OLP population that developed oral cancer compared to the OLP population without oral cancer (P = 0, 013), and healthy control subjects (P = 0, 0004). Conclusion: Based on the obtained results, it can be concluded that there is a significant difference in the level of serum vitamin D concentration between the subjects with OLP and the healthy control group. The exact mechanism of binding of vitamin D and OLP remains unknown. Future research on a larger sample is needed to determine their association.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA