Naslov
APOPTOSIS IN BENIGN GLIOMAS AND METASTATIC BRAIN TUMORS - PILOT STUDY

Autori
Ožegović, M. ; Talan Hranilović, J.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
7th LJUDEVIT JURAK INTERNATIONAL SYMPOSIUM ON COMPARATIVE PATHOLOGY BOOK OF ABSTRACTS / Belicza Mladen - Zagreb : Foto Quick, 1996

Skup
7th LJUDEVIT JURAK INTERNATIONAL SYMPOSIUM ON COMPARATIVE PATHOLOGY

Mjesto i datum
Zagreb, Hrvatska, 07.06.1996. - 08.06.1996

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
APOPTOSIS; BENIGN GLIOMAS; METASTATIC BRAIN TUMORS

Sažetak
Apoptosis is programmed cell death, control mechanism of cell elimination, process with genetic surveillance. It is energy dependent process that can be initiated, inhibited and modified with different exogenic and endogenic factors. In the recent literature there is small number of information about researches on human material and very small number of information about findings of apoptosis in primary tumors of CNS. This work is pilot study of research the apoptosis in pilocytic astrocytoma as prototype of primary benign gIioma and in metastatic brain tumors. It is known that the pilocytic astrocytoma is slowly growing benign glioma (grade I) and we were interested if the control mechanism of the growth of the tumor is in domain of apoptosis. Bioptic material was analyzed histologically in 30 cases and was treated stereologically in order to determine the volume density of apoptotic cells at this moment. The results show that apoptotic cells were not found in the group of pilocytic astrocytoma and that the largest volume density of apoptotic cells was in the group of metastatic brain tumor - type adenocarcinoma and smaller one in the group of metastatic brain tumor - type solid carcinoma.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA