Naslov
The duodenal-jejunal bypass liner for the treatment of type 2 diabetes mellitus and/or obesity: a systematic review.

Autori
Zechmeister-Koss, Ingrid ; Huić, Mirjana ; Fischer, Stefan

Izvornik
Obesity surgery (0960-8923) 24 (2014), 2; 310-323

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
duodenal-jejunal bypass liner ; type 2 diabetes mellitus ; obesity ; systematic review

Sažetak
This systematic literature review applies the GRADE approach to evaluate the efficacy and safety of the duodenal-jejunal bypass liner (DJBL) for the treatment of (a) patients with obesity ≥ grade II (with comorbidities) and (b) patients with type 2 diabetes mellitus + obesity ≥ grade I. We included ten studies with a total of 342 patients that primarily investigated a prototype of the DJBL. In high-grade obese patients, short-term excess weight loss was observed. For the remaining patient-relevant endpoints and patient populations, evidence was either not available or ambiguous. Complications (mostly minor) occurred in 64-100% of DJBL patients compared to 0-27% in the control groups. Gastrointestinal bleeding was observed in 4% of patients. We do not yet recommend the device for routine use.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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