Naslov
FTO gene association with depression – Does FTO gen affect obesity in patients with depression

Autori
Popović, Ana Marija ; Mustač, Filip ; Matovinović, Martina ; Marčinko, Darko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract Book (International Neuropsychiatric Congress. Online) / Demarin, Vida ; Budinčević, Hrvoje - Zagreb : International Institute for Brain Health, 2022, 39-40

Skup
61st International Neuropsychiatric Congress “Mind & Brain”

Mjesto i datum
Online, 26.05.2022. - 29.05.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
FTO gene, obesity, depression
(FTO gene polymorphism, obesity, depression)

Sažetak
Depression is a complex psychiatric disorder following many comorbidities such as diabetes, insulin resistance and obesity. Depression during childhood is associated with increased body mass index (BMI), while depression increases the odds of obesity, leading to major depressive disorders (MDD). The use of antidepressants may be associated with weight gain in terms of suppressing satiety and diminished physical activity, and fatigue by decreased motor activity. Patients with depression are more likely to be obese, whereas carriers of the risk allele of the FTO rs 9939609 are particularly prone to higher BMI. Further studies are needed in the field of the epigenetic individual approach that would include the recommendation of diet and medications that can influence expression and reduce the negative effect of risk alleles FTO gene on BMI.

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne prirodne znanosti, Kliničke medicinske znanosti

Napomena
Ana Marija Popović je prezentirala poster.

POVEZANOST RADA