Naslov
Impact of Consensus Definitions on Identification of Glomerular Lesions by Light and Electron Microscopy

Autori
Haas, Mark ; Mirocha, James ; Amann, Kerstin ; Bajema, Ingeborg M. ; Barisoni, Laura ; Becker, Jan Ulrich ; Jennette, J. Charles ; Joh, Kenuske ; Galešić Ljubanović, Danica ; Roberts, Ian S.D. ; Roelofs, Joris J. ; Sethi, Sanjeev ; Suarez, Raul ; Zeng, Caihong ; Seshan, Surya V.

Izvornik
Kidney International Reports (2468-0249) 7 (2022), 1; 78-86

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
electron microscopy ; glomerulonephritis ; glomerulus ; kidney biopsy ; renal pathology

Sažetak
Introduction: In 2020, a working group of 13 renal pathologists published consensus definitions for 47 individual glomerular lesions found on light microscopy (LM) and 47 glomerular lesions and 9 normal structures found on electron microscopy (EM). Methods: To test the impact of these definitions on identification of these lesions and structures, 2 surveys were circulated to all members of the Renal Pathology Society (RPS), each having 32 images (19 LM, 13 EM) and accompanying questions with 5 multiple-choice answers, one being the consensus choice of the working group. The first survey (survey 1 [S1]), answered by 297 RPS members, was sent in September 2020, before publication of the consensus definitions. The second (survey 2 [S2]), with images of the same lesions and structures (but not the same images) and the same questions and multiple choices in different order, was sent in April 2020, 5 months after the publication of the definitions. Results: S2 was taken by 181 RPS members ; 64% also took S1 and 61% reported having read the definitions paper (def. paper). Mean agreement with the consensus answers increased modestly between the 2 surveys (65.2% vs. 72.0%, P = 0.097) ; the increase was greater and significant when only respondents to S2 who read the def. paper were considered (65.2% vs. 74.8%, P = 0.026). Furthermore, in S2 agreement with consensus answers was greater among respondents who read this paper versus those who did not (66.9% vs. 74.8%, P < 0.0001). Conclusions: Publication of the consensus definitions modestly improved interobserver agreement in identification of glomerular lesions.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA