Pregled bibliografske jedinice broj: 1195848
Characterization and evolution of centromere in nematodes of the genus Meloidogyne
Characterization and evolution of centromere in nematodes of the genus Meloidogyne, 2022., doktorska disertacija, Sveučilište Josipa Jurja Strossmayera u Osijeku, Sveučilište u Dubrovniku, Institut Ruđer Bošković, Osijek
CROSBI ID: 1195848 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Characterization and evolution of centromere in nematodes of the genus Meloidogyne
Autori
Despot-Slade, Evelin
Vrsta, podvrsta i kategorija rada
Ocjenski radovi, doktorska disertacija
Fakultet
Sveučilište Josipa Jurja Strossmayera u Osijeku, Sveučilište u Dubrovniku, Institut Ruđer Bošković
Mjesto
Osijek
Datum
26.01
Godina
2022
Stranica
229
Mentor
Meštrović Radan, Nevenka
Ključne riječi
centromere ; CenH3 ; centromeric DNA ; nematode ; Meloidogyne ; metapolycentromere ; beetle ; Tribolium castaneum ; satellite DNA ; Nanopore sequencing
Sažetak
Centromeres are chromosomal regions responsible for the faithful segregation of chromosomes. In contrast to conserved function, the centromere protein (CenH3) and associated repetitive DNA evolve rapidly. However, our study revealed preservation of the αCenH3 variant along with conserved 19-bp box sequence in rapidly evolved centromeric DNA in asexual Meloidoygne nematodes. A similar approach was applied to the beetle Tribolium castaneum and showed a metapolycentric centromere organization with extended centromere regions. Long-range Nanopore sequencing is optimized for further study of centromeric arrays in the genomes of Meloidogyne and Tribolium species.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
POVEZANOST RADA
Projekti:
IP-2014-09-3183 - Centromerna genomika beskralježnjaka (CENGEN) (Plohl, Miroslav, HRZZ - 2014-09) ( CroRIS)
HRZZ-IP-2019-04-4910 - (Epi)genomika i transkriptomika eukromatinskih satelitnih DNA u embriogenezi i razvoju (EpiTranSat) (Meštrović Radan, Nevenka, HRZZ - 2019-04) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Sveučilište u Dubrovniku,
Sveučilište J. J. Strossmayera u Osijeku
