Naslov
Basaloid squamous cell carcinoma of the larynx : a case report

Autori
Tomasović, Čedna ; Petric, Vlado ; Čupić, Hrvoje ; Ivkić, Mirko ; Krušlin, Božo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
8th Ljudevit Jurak International symposium on comparative pathology : book of abstracts / Krušlin, Božo ; Robić, Mirna - Zagreb, 1997

Skup
Ljudevit Jurak International symposium on comparative pathology (8 ; 1997)

Mjesto i datum
Zagreb, Hrvatska, 06.06.1997. - 07.06.1997

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
basaloid squamous cell carcinoma; larynx

Sažetak
We report two patients with basaloid squamous cell carcinoma (BSCC) of the larynx. Both patients were males ageing 62 and 65 years, respectively. They were heavy smokers and moderate drinkers. They presented with hoarseness of three months' duration and dysphagia. Patients presented in Stage I and 1V, respectively. One patient was treated by surgery including radical dissection of the neck and the other by partial laryngectomy. The later patient underwent surgery 5 years earlier, due to colorectal carcinoma. At present, the patients are well, with no signs of the disease 3 and 6 months after diagnosis. BSCC is a distinctive, rare, highly aggressive variant of squamous cell carcinoma that arises in a variety of anatomic sites, including the larynx. So far, less than 30 cases of BSCC of the larynx were reported in the literature.The tumours were composed of moderately pleomorphic basaloid cells forming nests, cords, and cribriform patterns. Foci of necrosis, and squamous differentiation as well as small cystic spaces containing mucinlike material, were also observed. Surface mucous showed squamous dysplasia. BSCC should be distinguished from adenoid cystic carcinoma and small cell carcinoma usually in routine hematoxylin and eosin stained sections, or in rare cases with the aid of immunohistochemical methods. Their distinction is very important because adenoid cystic carcinoma is much less aggressive than BSCC. A careful follow-up of the patients is clearly needed.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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