Naslov
Diagnostic Value of Cognitive-Registration Multiparametric Magnetic Resonance Guided Biopsy for the Detection of Prostate Cancer after Initial Negative Biopsy

Autori
Tomašković , Igor ; Pezelj , Ivan ; Bolanča Čulo , Karolina ; Novosel , Luka ; Nikles , Sven ; Tomić , Miroslav ; Reljić , Ante ; Katušić , Josip ; Knežević , Matej ; Pirša , Matea ; Keušlin , Božo ; Ulamec , Monika ; Ružić , Boris

Izvornik
Acta clinica Croatica. Supplement (0353-9474) 57 (2018); 45-50

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Prostate cancer ; Multiparametric magnetic resonance ; Biopsy

Sažetak
The aim of this prospective clinical study was to determine the detection rate of prostate cancers by multiparametric magnetic resonance and transrectal ultrasound (mpMRI-TRUS) cognitive fusion biopsies in patients with a previously negative TRUS-guided biopsy. Between 1 October 2016 and 1 July 2017, in 101 consecutive patients with elevated antigen (PSA) and/or positive digital rectal examination and after a negative first TRUS biopsy, a second, repeated prostate biopsy was performed. In 24 patients, cognitive fusion mpMRI-TRUS biopsy of the prostate with 8-10 system cores and 1-3 target biopsies was performed, in line with the European Association of Urology guidelines. In 77 patients, only a classic, repeated TRUS guided biopsy was performed. In patients with mpMRI, the detection rate according to PIRADS-v2 reporting system was: PIRADS 1, n = 0 ; PIRADS 2, n = 0 ; PIRADS 3, n = 0 ; PIRADS 4, n = 6/8 (75%) ; and PIRADS 5, n = 2/3 (67%). In the group of patients with MR-TRUS cognitive fusion biopsy, the prostate cancer detection rate was 8/24 (33%), while in the control group the detection rate was 12/77 (16%), which was statistically significant (t test, p = 0.037, CI 95% is 0.01 to 0.37). Patients with PIRADS ≤ 3 (54%) could have avoided the biopsy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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