Naslov
Investigating copper nanoparticle-derived cytogenetic abberations in early life stages of sea urchin Sphaerechinus granularis

Autori
Čarapar, Ivana ; Jaklin, Andrej ; Lyons, Daniel Mark

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
6. simpozij studenata doktorskih studija PMF-a : knjiga sažetaka = 6th Faculty of Science PhD student symposium : book of abstracts / Schneider, Petra - Zagreb : Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, 2022, 304-305

ISBN
978-953-6076-93-2

Skup
6. Simpozij studenata doktorskih studija PMF-a = 6th Faculty of Science PhD Student Symposium

Mjesto i datum
Zagreb, Hrvatska, 23.04.2022. - 24.04.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Copper nanoparticles ; cytogenetic abberations ; Sphaerechinus granularis

Sažetak
Copper and copper oxide nanoparticles (CuNPs) are widely used in a broad range of industrial applications such as nanotechnology, medicine, biotechnology and environmental remediation [1]. The use of copper nanoparticles (CuNP) in anti- fouling formulations has been gaining popularity and that presents a direct route into marine environments where they can impact a wide range of organisms at all life stages, from embryos to adults [2, 3]. In this study, the effects of copper and copper oxide nanoparticles (Cu, CuO, Cu2O) on sea urchin Sphaerechinus granularis embryos were tested in terms of cytogenetic anomalies, as well as changes in mitotic activity. The morphological abnormalities that were scored included anaphase bridges, lagging chromosomes, acentric fragments, scattered chromosomes and multipolar spindles. While copper ions are known to be toxic to organisms and are often used as a positive control in bioassays, copper nanoparticles showed values close to those of Cu2+ ions, especially at higher copper concentrations of 2 and 5 mg/L. Furthermore, copper oxide nanoparticles were generally found to be less toxic than copper nanoparticles, with the most common abnormalities found being inhibition of mitotic activity and anaphase bridges. Differences in toxicity among the various types of nanoparticles was ascribed to their kinetics of dissolution and speciation although nanoparticle coating may also play a role. Ultimately, this work may indicate preferred chemical forms of copper nanoparticles for tailoring ship paints to maintain anti-fouling abilities over extended time periods.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Interdisciplinarne prirodne znanosti

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