Naslov
Herpes Simplex Encephalitis: A Case Report

Autori
Zahirović, David ; Dejhalla, Ema ; Zavidić, Tina

Izvornik
Journal of Clinical and Experimental Investigations (1309-6621) 13 (2022), 2; Em00796, 5

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Herpes simplex virus type 1 ; Encephalitis ; Diabetes mellitus type 1
(herpes simplex virus type 1 ; encephalitis ; diabetes mellitus type 1)

Sažetak
Herpes simplex virus encephalitis (HSVE) is an acute or subacute illness associated with focal or global cerebral dysfunction. It is caused by herpes simplex viruses belonging to either type 1(HSV-1) or type 2(HSV-2). Most of HSVE is caused by HSV-1. The most common manifestations include encephalopathy, fever, seizures, headaches, and focal neurological deficits. 49-year-old patient who has diabetes mellitus type 1, first presented with a fever, followed by a generalized epileptic seizure. In the Emergency Room a lumbar puncture was performed, and HSV-1 was detected in the cerebrospinal fluid. MR of the brain concluded that the changes correspond to the changes within HSV-1 encephalitis with a smaller area of hemorrhage. The patient was prescribed with acyclovir 3×10 mg/kg i.v. for three weeks. After antiviral therapy and glycemic control, the patient was discharged with antiepileptic, antihypertensive, antiulcer and antidiabetic drugs and indication to do a control EEG and infectologist exam with laboratory findings. HSVE has high morbidity and mortality, and the treatment of choice is acyclovir therapy

Izvorni jezik
Engleski

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