Naslov
Preimplantation Genetic Diagnosis

Autori
Markova-Car, Elitza ; Pavelić, Krešimir

Izvornik
Donald School Journal of Ultrasound in Obstetrics and Gynecology (0973-614X) 16 (2022), 1; 79-82

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Embryo, Microarray, Next generation sequencing, Preimplantation genetic diagnosis

Sažetak
Preimplantation genetic diagnosis (PGD) or preimplantation genetic screening (PGS) is an early form of prenatal diagnosis which allows that, before the pregnancy has begun, embryos can be tested for genetic disorders. The rationale behind the method lies in the removal of cells from early embryos and genetic analysis of these cells before being transferred to the uterus. This procedure offers an advantage for those couples having genetic disorders whose offspring has an increased risk of a specific genetic condition by helping in the delivery of a healthy baby or prevention of repeated spontaneous abortions. As a result, PGS has developed as a valuable tool for enhancing pregnancy success with assisted reproductive technologies. In fact, PGD may possibly be suggested for any disorder for which molecular testing can be performed.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA