Naslov
Neoadjuvant radiotherapy and chemotherapy in localy advanced rectal cancer

Autori
Fröbe, Ana ; Marić-Brozić, Jasmina ; Soldić, Željko ; Bolanča, Ante ; Zovak, Mario ; Jones, Glenn ; Rosenblatt, Eduardo ; Đaković, Nikola

Izvornik
Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti (1330-5301) 530 (2017), 44; 89-101

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neoadjuvant therapy ; locally advanced rectal cancer

Sažetak
At the Department of Oncology and Nuclear Medicine UHC “Sestre milosrdnice” patients who had advanced rectal cancer were treated with preoperative radiotherapy and chemotherapy, in cooperation with the IAEA and ESTRO. Fifteen patients who met the criteria and signed informed consent were included. Patients were randomized into two groups: Group 1: standard group, neoadjuvant approach (chemotherapy 5-FU / leucovorin concomitantly with radiotherapy (45-50 Gy in 25 fractions) ; Group 2: short course group, chemotherapy 5-FU / leucovorin with radiotherapy (25 Gy in 5 fractions). The main objectives were to determine the rate of resectability after completion of neoadjuvant therapy and to determine the percentage of local control and overall survival.

Izvorni jezik
Hrvatski, engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA