Naslov
Toxicology : Effects of age, sex and other factors

Autori
Telišman, Spomenka

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, pregledni

Knjiga
Encyclopaedia of Occupational Health and Safety, Vol.1

Urednik/ci
Stellman, Jeanne Mager

Izdavač
Međunarodna organizacija rada

Grad
Ženeva

Godina
1998

Raspon stranica
33.16-33.18

ISBN
92-2-109203-8

Ključne riječi
age, sex, dietary habits, smoking, alcohol, medications, concomitant exposure to other chemicals

Sažetak
There are often large differences among humans in the intensity of response to toxic chemicals, and variations in susceptibility of an individual over a lifetime. These can be attributed to a variety of factors capable of influencing absorption rate, distribution in the body, biotransformation and/or excretion rate of a particular chemical. Apart from the known hereditary factors which have been clearly demonstrated to be linked with increased susceptibility to chemical toxicity in humans, other factors include: constitutional characteristics related to age and sex ; pre-existing disease states or a reduction in organ function (non-hereditary, i.e., acquired) ; dietary habits, smoking, alcohol consumption and use of medications ; concomitant exposure to biotoxins (various microorganisms) and physical factors (radiation, humidity, extremely low or high temperatures or barometric pressures particularly relevant to the partial pressure of a gas), as well as concomitant physical exercise or psychological stress situations ; previous occupational and/or environmental exposure to a particular chemical, and in particular concomitant exposure to other chemicals, not necessarily toxic (e.g., essential metals).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA