Naslov
Intoxications in clinical settings

Autori
Potočnjak, Ines ; Klobučar, Iva ; Degoricija, Vesna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Arhiv za higijenu rada i toksikologiju, 72 (2021), Suppl 1 / - , 2021, 16-16

Skup
6th Croatian congress of toxicology with international participation (CROTOX 2021)

Mjesto i datum
Rabac, Hrvatska, 03.06.2021. - 06.06.2021

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
acute intoxication ; overdose ; poisoning ; substance abuse ; toxicology

Sažetak
Treating intoxicated patients is a daily challenge in hospital emergency departments (ED). Intoxicated patients often require toxin-specific diagnostic and medical treatment protocol. Our aim was to investigate the demographic characteristics, intentions, toxic agents, and outcomes in acutely intoxicated patients. We performed a prospective, observational study that included acutely intoxicated patients treated in the ED at the University Hospital Centre Sestre Milosrdnice, Zagreb, Croatia, during the years 2001, 2010, and 2015. A total of 1593 patients were included in the study (331 in 2001, 618 in 2010, 644 in 2015). According to gender, men were predominant (55.9, 65.2, and 70.7 %, respectively). Ethanol was the main intoxication substance (40.2, 69.4, and 75.8 % respectively). Anxiolytics were the main agent used in a suicide attempt, and the second most commonly used agent (46.5, 32, and 18.5 % respectively). During the years, there was a decline in suicide attempts (46.2, 22.2, and 17.1 % respectively). A total of 160 acutely intoxicated patients were treated in the Intensive Care Unit, i.e. 67 (20.2 %), 49 (7.9 %), and 44 (6.8 %), respectively. In-hospital mortality was low (0.9 % of all patients in 2001, 0.8 % in 2010, and 0.8 % in 2015). Interestingly, this study had a low mortality rate due to the good safety profile of substances. It is important to know which substances are commonly used in a population in order to apply diagnostic and treatment protocols. However, the challenge are new substances for which there are still no quick diagnostic tests or specific treatments available.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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