Naslov
Lobular Neoplasia-The Diagnosis and Treatment -A Case Report

Autori
Ranogajec, Irena ; Moslavac, Sandra ; Šarčević, Božena ; Latin, Branko ; Mušterić, Goran

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
SIS European Congresson Breast Diseases 6th Congress of The Croatian Senologic Society Book of Abstracts2015 ; 88 / - , 2015, 88-88

Skup
SIS European Congresson Breast Diseases, 6th Congress of The Croatian Senologic Society

Mjesto i datum
Opatija, Hrvatska, 22.10.2015. - 25.10.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Lobular neoplasia ; Breast ; FNA

Sažetak
Lobular neoplasia (LN) includes a range of changes within the breast lobules including atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS). An overall incidence is 3.8% with most of the cases occurring in premenopausal women. Most cases are present without any symptoms or are discovered as calcifications on mammogram or rarely with breast mass. Although treatment options of LN can range from follow-up with magnetic resonance imaging (MRI) to bilateral mastectomy and preventive usage of the hormonal therapy (tamoxifen) for five years, there is still no recommended standard treatment. We report a case of lobular neoplasia including its diagnostic and treatment procedure. A 54-year old patient came to our Polyclinic due to preventive examination. The radiologist performed ultrasound and mammography and indicated FNA of the inhomogeneous mass 300 mm in length in the right breast. The cytological diagnosis was suspected for malignancy and therefore biopsy was suggested. Due to clinical, radiological and cytological findings the surgeon decided to perform radical mastectomy with axillar dissection followed by breast reconstruction. The histopathological diagnosis of lobular neoplasia was confirmed. Recently molecular research showed that LN is not just high-risk factor for the development of bilateral breast carcinoma but also an non- obligate precursor of invasive lobular carcinoma. Despite the radical treatment option in our patient, there is still a risk for developing invasive breast carcinoma in another breast. Because of well known controversies in management of LN, there is significant need for multidisciplinary and individual approach in treating the women with lobular neoplasia, summarizing all medical findings and factors, including a patient requests.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA