Naslov
GENDER DIFFERENCE IN PREVALENCE AND RISK FACTORS OF ARTERIAL HYPERTENSION AND RESISTANT HYPERTENSION IN RENAL TRANSPLANT RECIPIENT

Autori
Vuckovic, M. ; Raos, H. ; Bucan Nenadic, D. ; Culjak, Z. ; Radic, J.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Skup
29th European Meeting on Hypertension and Cardiovascular Protection (ESH 2019)

Mjesto i datum
Milano, Italija, 21.06.2019. - 24.06.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
hypertension, resistant hypertension, kidney transplant recipient

Sažetak
Objective: Arterial hypertension (HT) is common in renal transplant recipients (RTRs) and control of HT is not optimal in this population. Previous study showed that metabolic syndrome and immunosuppressive drugs are emerged as strong predictors of poor HT control. Also, regardless of achieved renal function, RTRs may experience resistant hypertension (RAH). The aim of this study was to analyse gender differences in prevalence of HT and RH and identified possible factors associated with resistant HT in male and female RTRs. Image Design and method: 89 RTRs, 48 (53.93%) men and 41 (46.07%) women, aged 59.31 years were included. For each RTRs patient data about number and type of antihypertensive drugs, age, gender, body weight and height were collected. Also, serum creatinine were measured and body mass index (BMI) and glomerular filtration (GF) was calculated. The Agedio B900 device was used to measure arterial pressure. Values of peripheral and central systolic as well as peripheral and central diastolic arterial pressure were measured. Tanita MC780 Multi Frequency segmental body composition analyser was used to measure content of body fat, muscle mass and visceral fat each study subject. Results: 42 (93.33%) male and 36 (90%) female patients have AH, but significant difference in prevalence of AH among those two groups was not found. Therefore, 32 (71.11 %) male patient and 21 (52.50%) female patients have RAH, but significant difference in prevelance of AH among those two groups of RTRs was not found. Also, result showed that male patiens have statistically higher fat mas, muscle mass, content of visceral fat and creatinine level, but statistically differences in GF and blood pressure paramates were not found (Table 1.) Conclusions: There is high prevalence of AH and RAH among RTRs. Male RTRs have significantly more fat and more visceral fat then female patients but they did not have significantly higher blood pressure or GF. Possible explanation for this findings could be that in RTRc other risk factors (such are immunosuppressive drugs) can influence blood pressure more than fat tissue.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA