Naslov
Ion release and hydroxyapatite precipitation of resin composites functionalized with two types of bioactive glass

Autori
Par, Matej ; Gubler, Andrea ; Attin, Thomas ; Tarle, Zrinka ; Tarle, Andro ; Tauböck, Tobias T.

Izvornik
Journal of dentistry (0300-5712) 118 (2022); 103950, 11

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
resin composites ; bioactive glass ; hydroxyapatite ; calcium phosphate ; fluoride

Sažetak
Objectives: To prepare experimental composites with bioactive glass (BG) and investigate their release of calcium (Ca), phosphate (PO4), and fluoride (F), as well as pH changes and apatite precipitation after immersion. Methods: Experimental composites were prepared with 0, 10, or 20 wt% of either BG 45S5 or a customized low- Na F-containing BG. Three commercial ion-releasing materials were used for reference. Material specimens were immersed in lactic acid (pH = 4.0) and artificial saliva (pH = 6.4). Ion concentrations (atomic absorption spectrometry for Ca, UV–vis spectrometry for PO4, and ion-selective electrode for F) and pH were measured after 4, 8, 12, 16, 20, 24, 28, and 32 days. After immersion, composite specimens were analyzed using scanning electron microscopy (SEM) and Fourier-transform infrared (FTIR) spectroscopy. Results: Material- dependent concentrations of Ca, PO4, and F were measured in the lactic acid solution, while a decrease of Ca and PO4 concentrations was observed in artificial saliva. The uptake of ions from artificial saliva indicates their precipitation on specimen surfaces, which was supported by the results of SEM and FTIR investigations. In experimental composites functionalized with both bioactive glass types and a commercial “alkasite” material, apatite was precipitated not only in artificial saliva but also in the lactic acid solution. Conclusions: Experimental BG-containing composites and selected commercial restorative materials demonstrated the potential for releasing multiple ion types and increasing pH. Clinical significance: The observed effects can be beneficial for preventing demineralization and promoting remineralization of dental hard tissues, while apatite precipitation can additionally help in sealing marginal discontinuities.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA