Naslov
Classification of porcine reproductive and respiratory syndrome virus in Ontario using Bayesian phylogenetics and assessment of temporal trends

Autori
Melmer, Dylan John ; Friendship, Robert ; O'Sullivan Terri ; Greer, Amy ; Novosel, Dinko ; Ojkić, Davor ; Poljak, Zvonimir

Izvornik
Canadian journal of veterinary research-revue canadienne de recherche veter inaire (0830-9000) 85 (2021); 83-92

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
PRRSV ; Bayesian phylogeny ; Ontario

Sažetak
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important swine viruses globally, including in Ontario, Canada. Understanding the evolution and relation of the various PRRSV genotypes in Ontario can provide insight into the epidemiology of the virus. The objectives of this study were to i) describe the variability of PRRSV genotypes in Ontario swine herds, and ii) evaluate possible groupings based on PRRSV genomic data. Virus open reading frame 5 (ORF-5) sequences collected from 2010 to 2018 were obtained from the Animal Health Laboratory, University of Guelph and Bayesian phylogenetic models were created from these. The PRRSV population of Ontario was then categorized into 10 distinct clades. Model comparisons indicated that the model with a constant population assumption fit the data best, which suggests that the net change in the PRRS virus variation of the entire population over the last decade was low. Nonetheless, viruses grouped into individual clades showed temporal clustering during distinct time intervals of the entire study period (P < 0.01).

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA