Naslov
Neutrophil‐to‐lymphocyte and platelet‐to‐lymphocyte ratios as prognostic biomarkers in polycythemia vera
(Neutrophil‐to‐lymphocyte and platelet‐to‐ lymphocyte ratios as prognostic biomarkers in polycythemia vera)

Autori
Krečak, Ivan ; Holik, Hrvoje ; Morić Perić, Martina ; Zekanović, Ivan ; Coha, Božena ; Valovičić Krečak, Marija ; Gverić‐Krečak, Velka ; Lucijanić, Marko

Izvornik
International journal of laboratory hematology (1751-5521) 44 (2021), 4; E145-e148

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo uredniku, znanstveni

Ključne riječi
neutrophil-to-lymphocyte ratio ; platelet-to-lymphocyte ratio ; polycythemia vera ; survival ; thrombosis.

Sažetak
Neutrophil-to-lymphocyte ratio (NLR) and platelet- to-lymphocyte ratio (PLR) emerged as rapidly available biomarkers of inflammation and advanced atherosclerosis. This retrospective multicenter study investigated whether NLR and PLR may also improve prognostication in patients with polycythemia vera (PV), a hematological neoplasm with significant cardiovascular morbidity. In this study, we show that higher baseline PLR in PV may be associated with an increased risk of future thrombosis and death in PV. Higher PLR may, therefore, represent a rapidly available biomarker which could help to identify PV patients under an increased risk of inferior outcomes.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA