Naslov
Comparison of the Schein and OSDI questionnaire as indicator of tear film stability in patients with schizophrenia

Autori
Bakija, Ivana ; Kaštelan, Snježana ; Filipčić, Igor ; Bogadi, Marija ; Šimunović Filipčić, Ivona

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Psychiatria Danubina, 33 (2021), Suppl 2 / - , 2021, 169-170

Skup
29th Danubian psychiatric symposium and IX Croatian congress on psychopharmacotherapy

Mjesto i datum
Online ; Zagreb, Hrvatska, 18.03.2021. - 20.03.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
schizophrenia ; Schein questionnaire ; OSDI questionnaire ; dry eye ; tear film stability ; TBUT

Sažetak
Aim: The aim of this research was to determine which of two chosen questionnaires for subjective symptoms of dry eye (Ocular Surface Disease Index and Schein questionnaire) is more reliable in the assessment of dry eye in patients with schizophrenia. Subjects and Methods: Our research included 80 patients (160 eyes) of both sexes with schizophrenia ranging between the age of 25 and 55 who have been taking one of three antipsychotic drugs namely clozapin, olanzapin, quetiapin for five or more years and were in a stable phase of the disease or remission . All participants were required to satisfy all included and excluded criteria. They all filled out the Schein and OSDI questionnaires for assessment of subjective symptoms. Tear break-up time test for objective evaluation of tear film stability was also performed. In order to determine the correlation between two subjective and objective tests we calculated Spearmans correlation coefficients. Results: Obtained results of the correlation between OSDI questionnaire and TBUT test for the right eye was r = -0.73 ; p < 0.01 and for the left eye was r = -0.72 ; p < 0.01. Results of the correlation between Schein questionnaire and TBUT test for the right eye was r = -0.62 ; p < 0.01and for the left eye was r = -0.60 ; p <0.01. A detailed analysis shows that there are no statistically significant differences between the correlations. Both subjective questionnaires are statistically significantly and negatively related to the TBUT test, showing that an increase in the results on the OSDI and Schein's questionnaires led to the decreases in the results on the TBUT test. Conclusion: In patients with schizophrenia OSDI and Schein questionnaire are equally reliable in the assessment of subjective symptoms of DED. Considering that OSDI is more common in clinical practice, it is also recommended for use in patients with schizophrenia.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA