Naslov
Raynaud's phenomenon in children and adolescents

Autori
Škreb, Nikola

Vrsta, podvrsta i kategorija rada
Ocjenski radovi, diplomski rad, diplomski

Fakultet
Medicinski fakultet

Mjesto
Zagreb

Datum
17.07

Godina
2020

Stranica
52

Mentor
Jelušić, Marija

Ključne riječi
Raynaud's phenomenon ; CCTT ; children, adolescence

Sažetak
Raynaud's phenomenon (RP) is a condition characterized by increased and exaggerated vasoreactivity to cold temperatures and mental stress. Computerized colour telethermography (CCTT) is an established diagnostic procedure in clinical practice that is used for assessment and follow-up of patients with microcirculatory disorders. Objective of this study was to analyze the diagnostic value of CCTT and its use in the diagnosis of RP. CCTT results were interpreted to determine occurrence and prevalence of both primary Raynaud's phenomenon (PRP) and secondary Raynaud's phenomenon (SRP) according to sex and age. We conducted a retrospective investigation and analysis of medical records and CCTT results from 464 pediatric patients under the clinical and anamnestic suspicion of RP in a 14-year period. Prevalence of PRP and SRP was calculated in the total targeted pediatric sample as well as separately female and male prevalence of both disease variants. Patients were categorized into three different age groups to determine differences in age distribution. Pearson's chi- squared test was used to assess the correlation between sex and case distribution, and correlation between age and case distribution. Results showed prevalence of 12.93% of PRP and prevalence of 25.43% of SRP in the targeted sample. There was a clear difference in sex distribution, with males showing higher prevalence of SRP and negative cases, and females showing higher prevalence of PRP. Correlation between sex and case distribution did not prove to be statistically significant (p=0.26). Late adolescence has been demonstrated as the most affected group, showing significantly higher prevalence of both PRP and SRP and significantly lower prevalence of negative cases. This age group has also been proven as statistically significant factor (p=0.0024) for the occurrence of RP when compared to early adolescence. Based on these results, there is increased risk of RP occurrence in the female population and in late adolescence.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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