Pregled bibliografske jedinice broj: 1171826
Stability Study of Losartan Potassium and Hydrochlorothiazide tablets
Stability Study of Losartan Potassium and Hydrochlorothiazide tablets // Farmacevtski Vestnik 54 (Special Issue) / Mrhar, Aleš (ur.).
Ljubljana, 2003. str. 491-492 (poster, međunarodna recenzija, prošireni sažetak, znanstveni)
CROSBI ID: 1171826 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Stability Study of Losartan Potassium and
Hydrochlorothiazide tablets
Autori
Lusina, Maja ; Cindrić, Tanja ; Tomaić, Jadranka ; Ballian, Davorka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, prošireni sažetak, znanstveni
Izvornik
Farmacevtski Vestnik 54 (Special Issue)
/ Mrhar, Aleš - Ljubljana, 2003, 491-492
Skup
5th Central European Symposium on Pharmaceutical Technology and Biotechnology
Mjesto i datum
Ljubljana, Slovenija, 25.09.2003. - 27.09.2003
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
losartan potassium ; hydrochlorothiazide ; stability testing ; packaging
Sažetak
Stability study of losartan/hydrochlorothiazide tablets consisted of three steps: stress test (forced degradation study), preliminary testing (selection of packaging) and formal stability testing. The results of stress test suggested that losartan/hydrochlorothiazide tablets are sensitive to moisture. Additional preliminary testing was performed in order to select appropriate packaging for losartan/hydrochlorothiazide tablets. OPA/Al/PVC//Al blisters were found to provide adequate protection for the product. Based on the first 6 months of the formal stability study, a shelf life of 24 months was proposed. Losartan/hydrochlorothiazide tablets in OPA/Al/PVC//Al blisters are demonstrated to be chemically, physically and microbiologically stable.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Ustanove:
PLIVA HRVATSKA d.o.o.
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
