Naslov
Consumption of plasma derivates in Croatia

Autori
Jaklin, Gordana ; Golubić Ćepulić, Branka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Skup
15th ISBT European Regional Conference

Mjesto i datum
Atena, Grčka, 2.-6.7

Vrsta sudjelovanja
Poster

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
plasma derivates

Sažetak
A increasing consumption of plasma derivates, their limited supply and insufficient national reserves are problems that Croatia is faced with nowadays, as well as many other countries. In 2003 a study was carried out regarding the usage of plasma derivates. As many as 34 health institutions took part having the capacity of 15487 acute beds out of a total of 16279. The data regarding the use of plasma derivates were collected as follows: albumin, I.V. gamma globulin, and concentrate of coagulation factor VIII in two periods of time. We divided institutions into three categories: clinical hospitals, general hospitals with the capacity of 400–600 beds and general hospitals with the capacity of 100–400 beds. Institutional practice patterns regarding the use plasma derivates were compared among them. The parameters considered were the total consumption of plasma derivates, consumption per bed and consumption per inhabitant. Data on the use of plasma derivates was obtained from hospital transfusion departments and pharmacies across the country. We compared our data with similar study carried out in 1997. The consumption of albumin was 441.44kg or 98kg/million inhabitants in 2003 and consumption per bed for the first category institutions was in range 14.27–72.27kg with the median being 39.42, for the second category the range was 1.24–44.64kg with the median being 4.36, while for the third category the range was 0.32–23.13kg with the median being 6.63. In 1997 in Croatia the consumption of albumin was 436.50kg or 97kg/million inhabitants. The consumption of I.V. gamma globulin was 59.92kg or 13.32 kg/million inhabitants in 2003 and the consumption per bed for the first category institutions was in range 0.03g–8.89g. with the median being 2.78, for the second category was in range 0.03–3.95 g. with the median of 1.56 and for the third category was in range 0.00–12.75 with the median 1.56g. In 1997 in Croatia the consumption of I.V. gamma globulin was 22.20kg or 4.93/million inhabitants. The consumption of the concentrate of factor VIII was 8807.000IU or 1.96IU per inhabitant in 2003. 1539.500IU, i.e. 17.48%, was a recombinant factor VIII. In 1997 the consumption of factor VIII was 4876.350IU or 1.08IU per inhabitant. Discussion: The use of albumin showed stagnation. However, the use of I.V. gamma globulin increased 2.6 times and the use of the concentrate of factor VIII increased 1.8 times if compared with the results in 1997. Self-sufficiency has not been reached in plasma derivates in Croatia We needed 20000L plasma for gamma globulin and 58000L plasma for concentrate of factor VIII for the level of usage of these plasma derivates in 2003. Significant differences in the level of usage among hospitals have been observed. These reflected a considerable difference in hospital policy regarding the use of these products in defined clinical settings. Therefore, we would recommend that the National Society sets out guidelines for the use of the products.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

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