Pregled bibliografske jedinice broj: 1165627
Recurrence of tumor flare reaction in a chronic lymphocytic leukemia patient during chlorambucilrituximab treatment 6 years after lenalidomide
Recurrence of tumor flare reaction in a chronic lymphocytic leukemia patient during chlorambucilrituximab treatment 6 years after lenalidomide // Open Access Journal of Biomedical Science, 4 (2021), 3; 1098-1099 doi:10.38125/oajbs.000310 (međunarodna recenzija, članak, znanstveni)
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Naslov
Recurrence of tumor flare reaction in a chronic
lymphocytic leukemia patient during
chlorambucilrituximab treatment 6 years after
lenalidomide
Autori
Živković, Neno ; Gjadrov, Koraljka ; Dubravčić, Klara ; Bašić-Kinda, Sandra ; Aurer, Igor ;
Izvornik
Open Access Journal of Biomedical Science (2690-487x) 4
(2021), 3;
1098-1099
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
tumor flare reaction ; chronic lymphocytic leukemia ; rituximab ; lenalidomide
Sažetak
In chronic lymphocytic leukemia, tumor flare reactions, characterized by sudden increase in tumor lesions caused by host immune effector cell infiltration, have been described exclusively after treatment with immunomodulators, most frequently lenalidomide. Here we describe a patient who had recurrence of tumor flare 6 years after the initial event, during treatment with rituximab and chemotherapy. This case report suggests that lenalidomide causes a long-lasting effect on lymph node microenvironment and host T cells.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb