Pregled bibliografske jedinice broj: 1165525
New Approaches to the Synthesis of 2-Imino-penam Derivatives
New Approaches to the Synthesis of 2-Imino-penam Derivatives // Xth European Symposium on Organic Chemistry
Basel, Švicarska, 1997. str. 64-Book of Abstrect (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1165525 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
New Approaches to the Synthesis of 2-Imino-penam Derivatives
Autori
Herak, Jure ; Vinković, Mladen
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
Xth European Symposium on Organic Chemistry
Mjesto i datum
Basel, Švicarska, 1997
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
(5R ; 6S)-2-benzylimino-3-isopropylidene-penams ; benzylamide of penicillanic acid sulfoxide, reductive rearengement ; 1H-NMR ; X-ray
((5R ; 6S)-2-benzylimino-3-isopropylidene-penams ; benzylamide of penicillanic acid sulfoxide ; reductive rearengement ; 1H-NMR ; X-ray)
Sažetak
A novel and simple procedure for preparation of (5R, 6S)-2-benzylimino-6-bromo-3-isopropylidene-penam 2 and (5R, 6Sj-2-benzylimino-3-isopropylidene-penam 8 is described. The 2-imino-penam derivatives are prepared by modification of the Cooper reductive rearrangement of 3a benzylamide of penicillanic acid sulfoxides. The absolute configurations of starting sulfoxides and iminoproducts are assigned on the basis of 1H-NMR spectroscopic studies and verified by X-ray structure analysis of sulfoxide 3b and imino- penam 8.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Pliva-Istraživački institut
