Naslov
Severe Glyphosate - Surfactant Herbicide Poisoning; Successful Treatment - Case Report

Autori
Ninčević, Željko ; Ninčević, Jasna ; Gabelica, Maja ; Šundov, Željko ; Puljiz, Željko ; Gabelica, Mirko

Izvornik
MOJ addiction medicine & therapy (2573-2935) 4 (2017), 1; 202-204

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cardiovascular collapse, anuric acute renal failure, altered consciousness, severe poisoning, supportive treatment

Sažetak
Glyphosate-surfactant herbicide is one of the most frequently used herbicides. When large volumes of concentrates are ingested intentionally, it can generate fatal symptoms that are refractory to treatment. We present a case of a 45-year-old male who suffered from psychosis and deliberately drank a ½-liter of glyphosate-surfactant herbicide. His consciousness deteriorated into a coma, and he developed ARDS. Cardiovascular collapse developed. Acute renal failure, hyperkalemia and metabolic acidosis also developed. He was admitted to the intensive care unit. Orotracheal intubation was performed and mechanical ventilation was initiated. Infusions of dopamine and norepinephrine were also started. Continuous veno- venous hemodiafiltration was started 11 hours after ingestion and was performed for 5 days. Intermittent daily two-hour dialysis was performed for further 18 days. His renal function had fully recovered. He was mechanically ventilated for 9 days. After treatment, he was discharged to go home fully recovered with no neurological deficits. This is a case of severe glyphosate- surfactant herbicide poisoning which was successfully cured by supportive treatment and CVVHDF. According to the literature this is among the largest ingestion that patient survived.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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