Pregled bibliografske jedinice broj: 1165304
Stereoselective Cyclization and Ring Opening Reactions of and 2-Azacepham Sulfoxides
Stereoselective Cyclization and Ring Opening Reactions of and 2-Azacepham Sulfoxides // IXth European Symposium on Organic Chemistry
Varšava, Poljska, 1995. str. 119-Book of Abstract (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1165304 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Stereoselective Cyclization and Ring Opening Reactions of and 2-Azacepham Sulfoxides
Autori
Herak, Jure ; Vinković, Mladen ; Lukić Irena
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
IXth European Symposium on Organic Chemistry
Mjesto i datum
Varšava, Poljska, 1995
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Stereoselective cyclization ; 2-Azacepham sulfoxides
Sažetak
The enantiomerically pure 2-azacepham sulfoxide 2a was synthesized by stereocontrolled intramolecular cyclization of sulfinates 3 or sulfinamides 8 in the presence of dry hydrogen chloride followed by triethylamine. The cyclization accrued via equilibrated mixtures of sulfinyl chlorides, which presence was confirmed by chemical transformations. The absolute configuration of the sulfinic acid 9a as a product of their hydrolysis was determinate by a single crystal X-ray analysis. Synthesis and ring opening of substituted 2-azacephams via equilibrated mixtures of sulfinyl chlorides were performed
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Pliva-Istraživački institut
