Naslov
Supramolecular Control of Reactivity in the Solid State

Autori
Kralj, Magdalena ; Lukin, Stipe ; Miletić, Goran ; Halasz, Ivan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
IV. simpozij supramolekulske kemije (SupramolChem2021)

Mjesto i datum
Zagreb, Hrvatska, 10.12.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
mechanochemistry ; cocrystals ; salts ; desmotrpes ; polymorphs ; Knoevenagel condensation ; solid state reactions ; reaction kinetics

Sažetak
Mechanochemistry is becoming recognized as a technique because it can promote solid-state reactions quickly and quantitatively, even on a large scale, but is also enabling access to processes and products usually not feasible in solution [1, 2]. Multicomponent solids, like cocrystals have been recognized and used to execute solid state reactions selectively and efficiently. Building on these recent advances, herein we employ real-time in situ Raman spectroscopy monitoring [3, 4] to explore the possibilities of manipulating the reaction kinetics and chemical reactivity of the Knoevenagel condensation in solid state. We emphasize in particular reaction paths and product selectivity that can be explored in the solid state by applying principles of crystal engineering [5, 6] through the use of polymorphs, desmotropes, cocrystals, or salts.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

Napomena
Poster napravljen prema radu:
Kralj, Magdalena; Lukin, Stipe; Miletić, Goran;
Halasz, Ivan. Using desmotropes, cocrystals and
salts for manipulating reactivity in
mechanochemical organic reactions // Journal of
organic chemistry, 86 (2021), 20; 14160-14168
doi:10.1021/acs.joc.1c01817
https://www.bib.irb.hr/1141161

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