Naslov
Prognostic significance of radiation induced lymphopenia in patients with high risk prostate cancer

Autori
Antunac, Katarina ; Suton, Petar ; Bilić-Knežević, Sara

Izvornik
Libri oncologici : Croatian journal of oncology (0300-8142) 46 (2018); 55-59

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
prostate cancer ; whole pelvis radiotherapy ; radiation induced lymphopenia

Sažetak
Lymphopenia is a known side-effect of radiotherapy but, being usually asymptomatic, its clinical value is just recently being recognized in the light of immunotherapy revival. Here we present clinical and laboratory data of 9 high-risk prostate patients that underwent whole pelvis radiotherapy combined with hormonal therapy. All patients experienced haemato- logical toxicity during their treatment, with lymphopenia being the most profound. In addition, all of them were asymptom- atic as regards to observed lymphopenia. After median follow up of 17 months 8/9 patients are still receiving hormonal treatment and have no evidence of their disease. The only patient with relapse discontinued hormonal therapy upon com- pletion of radiotherapy. Therefore, we could not show any detrimental effect of observed lymphopenia on the outcome of these 9 patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA