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Pregled bibliografske jedinice broj: 1164157

A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate

Žegarac, Miroslav; Lekšić, Edislav; Šket, Primož; Plavec, Janez; Devčić Bogdanović, Maja; Bučar, Dejan-Krešimir; Dumić, Miljenko; Meštrović, Ernest
A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate // CrystEngComm Journal, 2014 (2014), 16; 32-35 doi:10.1039/c3ce42013b (međunarodna recenzija, kratko priopcenje, znanstveni)

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Naslov
A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate

Autori
Žegarac, Miroslav ; Lekšić, Edislav ; Šket, Primož ; Plavec, Janez ; Devčić Bogdanović, Maja ; Bučar, Dejan-Krešimir ; Dumić, Miljenko ; Meštrović, Ernest

Izvornik
CrystEngComm Journal (1466-8033) 2014 (2014), 16; 32-35

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
sildenafil, acetylsalicylic acid, cocrystal, IDR

Sažetak
Cocrystallisation of sildenafil with acetylsalicylic acid yields a 1 : 1 sildenafil–acetylsalicylic-acid cocrystal, as well as a 1 : 1 : 1 cocrystal salt involving a sildenafil cation, acetylsalicylate and salicylic acid. The 1 : 1 acetylsalicylic-acid-based cocrystal exhibits an enhanced intrinsic dissolution rate, as compared to sildenafil citrate (the active ingredient of Viagra®).

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Ustanove:
Pliva-Istraživački institut,
Sveučilište u Rijeci - Odjel za biotehnologiju

Profili:

Avatar Url Edislav Lekšić (autor)

Avatar Url Miljenko Dumić (autor)

Avatar Url Maja Devčić Bogdanović (autor)

Avatar Url Ernest Meštrović (autor)

Avatar Url Miroslav Žegarac (autor)

Poveznice na cjeloviti tekst rada:

doi pubs.rsc.org

Citiraj ovu publikaciju:

Žegarac, Miroslav; Lekšić, Edislav; Šket, Primož; Plavec, Janez; Devčić Bogdanović, Maja; Bučar, Dejan-Krešimir; Dumić, Miljenko; Meštrović, Ernest
A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate // CrystEngComm Journal, 2014 (2014), 16; 32-35 doi:10.1039/c3ce42013b (međunarodna recenzija, kratko priopcenje, znanstveni)
Žegarac, M., Lekšić, E., Šket, P., Plavec, J., Devčić Bogdanović, M., Bučar, D., Dumić, M. & Meštrović, E. (2014) A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate. CrystEngComm Journal, 2014 (16), 32-35 doi:10.1039/c3ce42013b.
@article{article, author = {\v{Z}egarac, Miroslav and Lek\v{s}i\'{c}, Edislav and \v{S}ket, Primo\v{z} and Plavec, Janez and Dev\v{c}i\'{c} Bogdanovi\'{c}, Maja and Bu\v{c}ar, Dejan-Kre\v{s}imir and Dumi\'{c}, Miljenko and Me\v{s}trovi\'{c}, Ernest}, year = {2014}, pages = {32-35}, DOI = {10.1039/c3ce42013b}, keywords = {sildenafil, acetylsalicylic acid, cocrystal, IDR}, journal = {CrystEngComm Journal}, doi = {10.1039/c3ce42013b}, volume = {2014}, number = {16}, issn = {1466-8033}, title = {A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate}, keyword = {sildenafil, acetylsalicylic acid, cocrystal, IDR} }
@article{article, author = {\v{Z}egarac, Miroslav and Lek\v{s}i\'{c}, Edislav and \v{S}ket, Primo\v{z} and Plavec, Janez and Dev\v{c}i\'{c} Bogdanovi\'{c}, Maja and Bu\v{c}ar, Dejan-Kre\v{s}imir and Dumi\'{c}, Miljenko and Me\v{s}trovi\'{c}, Ernest}, year = {2014}, pages = {32-35}, DOI = {10.1039/c3ce42013b}, keywords = {sildenafil, acetylsalicylic acid, cocrystal, IDR}, journal = {CrystEngComm Journal}, doi = {10.1039/c3ce42013b}, volume = {2014}, number = {16}, issn = {1466-8033}, title = {A sildenafil cocrystal based on acetylsalicylic acid exhibits an enhanced intrinsic dissolution rate}, keyword = {sildenafil, acetylsalicylic acid, cocrystal, IDR} }

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