Naslov
Indirect effect of global warming on mammals physiological parameters via high temperature-stressed plant diet (TEMPHYS): Project presentation

Autori
Šola, Ivana

Izvornik
3rd International Conference on Plant and Molecular Biology Webinar

Vrsta, podvrsta
Ostale vrste radova, ostalo

Godina
2021

Ključne riječi
globalno zatopljenje ; biljna metabolomika ; fiziologija sisavaca
(global warming ; mammal physiology ; plant metabolomics)

Sažetak
With this project we want to address the chain interactions between temperature shift, plant biochemical traits and mammals (fed with those plants) physiology, employing targeted specific metabolomics approach for plant analyses, biosafety and bioactivity tests on mammals, and statistical data analyses and modelling in order to construct a model showing a tentative pattern of environment temperature indirect (through plant diet) effect on mammal physiology. Our strategy is to identify metabolites of plants that have been altered by high temperature (HT), to quantify the intensity of changes, and to correlate those with changes in the physiological parameters of mice fed by these plants. As a plant representative we will use Brassica oleracea botrytis var. cymosa (broccoli) seedlings and mature plants, and as a mammal representative a mouse strain Swiss Webster albino will be used. Additionally, for in vitro biosafety analyses the cell culture of human hepatocellular carcinoma (HepG2) and mouse embryonal fibroblasts (MEF) will be used. This type of research would serve as a basis (case study) for future studies in this field (other plant species and growth stages, additional biochemical and physiological traits in plants and animals), which we have in our plan for a longer period. The results of this project will further clarify whether the phytochemical ability of plant to adapt to HT (simulating global warming) will be crucial for its nutritional value and biological effects in mammals, i.e. mammal health status.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Interdisciplinarne prirodne znanosti

Napomena
Predstavljanje projekta u sklopu konferencije "3rd International Conference on Plant and Molecular Biology Webinar"

POVEZANOST RADA