Pregled bibliografske jedinice broj: 1161399
1-isothiazolidinone derivatives of azetidine-2-one, process for the preperation thereof and the use thereof
1-isothiazolidinone derivatives of azetidine-2-one, process for the preperation thereof and the use thereof
(1999)
CROSBI ID: 1161399 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
1-isothiazolidinone derivatives of azetidine-2-one, process for the preperation thereof and the use thereof
Autori
Herak, Jure
Broj patenta
EP0930313A1
Godina
1999
Datum patenta
21.07.1999.
Nositelj prava
PLIVA ; ZAGREB ; HRVATSKA, Zagreb, Hrvatska
Sažetak
The object of the present invention are novel compounds of azetidine-2-one substituted in 1-position with different isothiazolidinone radicals, as analogons of a beta-lactam structure, of the general formula I wherein R<1> represents a hydrogen or a halo atom, R<2> represents a hydrogen or a halo atom or a phthalimide group, R<3> represents a hydrogen or a halo atom, R<4> represents a hydrogen or a halo atom, R<5> represents a hydrogen atom, a lower linear or branched alkyl, aryl or aralkyl, or a radical containing a heterocycle with one or more heteroatoms, such as isoxazolyl or pyrazolyl, and n is 0, 1 or 2. The usefulness of these compounds as intermediates for the preparation of novel beta-lactam analogons or active substances in formulations for antimicrobial therapy is given.
Izvorni jezik
Engleski
Znanstvena područja
Kemija, Farmacija
